頭頸部扁平上皮癌における原発腫瘍切除と潜在性リンパ節検出のためのデュアルイメージングナノセンサーによる術中リアルタイムナビゲーション
- 産業ナノマテリアル研究所 バイオマテリアル分野
研究内容
アピールポイント
Currently, BCA-ICG is intravenously injected into patients to confirm cancer. But it is nonspecific accumulating in the lymph nodes. In this study, as shown in the picture above, it is expected to be able to resect the border of cancer after spraying on the surface of the skin without incision to determine the response within 30 min. It is possible to remove the sensor before penetration of the skin, thus minimizing the toxicity.
Until now, the sensor was used in the form of a spray. In the case of animals, the test was carried out by intravenously injecting and observing the sensor in the body. Our team works with the surgeon to try to obtain more accurate results by using the tissue removed from the patient during the operation without freezing.
特許
2014-09-23 Application granted (US20110213121A1) : Nanoparticle sensor for measuring protease activity and method for manufacturing the same
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